This webinar can be hosted dwell and accessible on-demand
Monday, December sixteenth, 2024
12:30 – 2:00 PM ET
Focused therapies are remodeling the medical discipline by enabling clinicians to exactly and successfully deal with sufferers with severe ailments. Nevertheless, many proteins, akin to these labeled as transcription elements, small GTPases, and phosphatases, have problem interacting with drug compounds. Because of this, scientists think about these targets undruggable.
On this webinar dropped at you by The Scientist, Andrew Tsourkas and Chris Parker will focus on how they’re turning the phrase “undruggable” on its head by using new approaches to focus on undruggable proteins concerned in most cancers, autoimmune ailments, and past.
Matters to be coated
- Engineering a system to ship antibodies and different protein-based concentrating on ligands into the cytosol to inhibit and degrade cancer-associated proteins
- Creating photoaffinity-based chemical proteomic methods to establish small molecule binding websites on proteins and utilizing this info to design chemical probes towards disease-relevant targets
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Andrew Tsourkas, PhD |
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Chris Parker, PhD |
